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Received February 5, 2002
Accepted April 15, 2002
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Mathematical Modeling of Penicillin G Extraction by a Bifunctional Surfactant in a Continuous Extraction Column
Department of Chemical Engineering, Kunsan National University, Miryong Dong, Kunsan, Chonbuk 573-701, Korea 1Glass Tower, 946-1, Daechi-3Dong, Kangnam-Ku, Seoul 135-708, Korea
lee40f@kunsan.ac.kr
Korean Journal of Chemical Engineering, September 2002, 19(5), 827-832(6), 10.1007/BF02706976
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Abstract
A bifunctional surfactant was used as a carrier of penicillin G for its continuous extraction by an emulsion liquid membrane without an extractant in a countercurrent extraction column of Oldshue-Rushton type. A permeation model was presented to describe transport mechanism of penicillin G in the continuous extraction system, including an axial dispersion model for the continuous phase and a mass transfer model for the dispersed emulsion phase. The mass transfer model describes the external mass transfer around the emulsion drop, the reaction at the_x000D_
external interface, the diffusion as well as the reaction equilibrium within the w/o emulsion drop, and the pH change of internal aqueous phase. Here, we considered three experimental variables: penicillin G concentration, pH of continuous phase and surfactant concentration. The calculated results from the permeation model fitted the experimental data well.
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References
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Lee SC, Lee WK, J. Chem. Technol. Biotechnol., 55, 251 (1992)
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Skelland AHP, Moeti LT, Ind. Eng. Chem. Res., 29, 2258 (1990)
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