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Conflict of Interest: In relation to this article, we declare that there is no conflict of interest.

Publication history: Received May 4, 2002
Accepted June 13, 2002

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Liquid Chromatographic Separation of Xylene Isomers on α-Cyclodextrin Bonded Phases

Manhoe Kim^† Douglas Way¹ Robert M. Baldwin¹

Department of Chemistry, Air Force Academy (R.O.K.), Cheong-ju, Chungbuk 363-849, Korea ¹Chemical Engineering Department, Colorado School of Mines, Golden, CO 80401, USA

manhoe@hanmail.net

Korean Journal of Chemical Engineering, September 2002, 19(5), 876-879(4), 10.1007/BF02706983

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Abstract

Mesoporous glass beads and silica were modified with α-cyclodextrin (CD) for the separation of xylene isomers by means of direct bonding, linking spacer group, and cross-linking agent. The separation efficiency of the α-CD modified silica particles was tested by using simple column chromatography. A strong inclusion complex formation of p-xylene was observed from the column packed with α-CD bonded phases. Spacer group and crosslinking agent decreased the formation of the inclusion complex of p-xylene and increased selectivity between m-xylene_x000D_ and o-xylene. The inclusion complex formation of p-xylene was strongly diminished when the mobile phase was switched from methyl alcohol to toluene. The column packed with the cross-linked α-CD bonded silica showed the best performance in the separation of xylene isomers.

Keywords

Mesoporous Glass Beads Silica α-Cyclodextrin Xylene Separation Chromatography Inclusion Complex

References

Armstrong DW, "Bonded Phase Material for Chromatographic Separation," U.S. Patent, 4,539,399 (1985)
Armstrong DW, Demond WJ, Chromatogr. Sci., 22, 411 (1984)
Armstrong DW, Demond W, Alak A, Anal. Chem., 57, 234 (1985)
Chen HL, Wu LG, Tan J, Zhu CL, Chem. Eng. J., 78(2-3), 159 (2000)
Kim YD, Lee JK, Cho YS, Korean J. Chem. Eng., 18(6), 971 (2001)
Lee CH, J. Appl. Polym. Sci., 26, 489 (1981)
Szejtli J, Chem. Rev., 98(5), 1743 (1998)
Wytcherley RW, McCandless FP, J. Membr. Sci., 67, 67 (1992)