Articles & Issues
- Language
- English
- Conflict of Interest
- In relation to this article, we declare that there is no conflict of interest.
- Publication history
-
Received May 3, 2002
Accepted November 5, 2002
-
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits
unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © KIChE. All rights reserved.
All issues
A Study of Direct Loading of Beta-Cyclodextrins on Glass Beads as Chromatographic Separators
Department of Chemistry, Air Force Academy (R.O.K.), Chungbuk 363-849, Korea 1Chemical Engineering Department, Colorado School of Mines, Golden, CO. 80401, USA
manhoe@hanmail.net
Korean Journal of Chemical Engineering, May 2003, 20(3), 528-531(4), 10.1007/BF02705560
Download PDF
Abstract
Beta-cyclodextrin (β-CD) was successfully loaded on the surface of glass beads without spacer group or cross-linking agent. The directly loaded β-CD was stable in toluene and methanol flows but critically hurt in more polar solvent such as water and dimethylformamide. Cross-linking could stabilize the directly bonded β-CD glass beads. Pore openings of cyclodextrin can be narrowed or blocked by end-capping agent, spacer groups, and cross-linking agents. The β-CD directly bonded glass beads have a capability to form inclusion complexes with larger host molecules because this method can avoid pore narrowing and blocking problems.
References
Anzai JI, Kobayashi Y, Ueno A, J. Appl. Polym. Sci., 31, 1199 (1986)
Armstrong DW, "Bonded Phase Material for Chromatographic Separation," U.S. Patent, No. 4,539,399 (1985)
Armstrong DW, Demond W, J. Chromatogr. A, 22, 411 (1984)
Armstrong DW, Demond W, Alak A, Anal. Chem., 57, 234 (1985)
Forgacs E, Cserhati T, "Molecular Basis of Chromatographic Separation," CRC Press LLC, New York, 122 (1997)
Janson JC, Korean J. Chem. Eng., 18(2), 149 (2001)
Kim YD, Lee JK, Cho YS, Korean J. Chem. Eng., 18(6), 971 (2001)
Krieg HM, Breytenbach JC, Keizer K, J. Membr. Sci., 164(1-2), 177 (2000)
Lee CH, J. Appl. Polym. Sci., 26, 489 (1981)
Miyata T, Iwamoto T, Uragami T, J. Appl. Polym. Sci., 51, 2007 (1986)
Moon JK, Keum DK, Lee WK, Korean J. Chem. Eng., 6(3), 172 (1989)
Sreenivasan K, J. Appl. Polym. Sci., 60(12), 2245 (1996)
Sreenivasan K, J. Appl. Polym. Sci., 70(1), 15 (1998)
Szejtli J, Chem. Rev., 98(5), 1743 (1998)
Zhao XB, He BL, React. Polym., 24(1), 1 (1994)
Armstrong DW, "Bonded Phase Material for Chromatographic Separation," U.S. Patent, No. 4,539,399 (1985)
Armstrong DW, Demond W, J. Chromatogr. A, 22, 411 (1984)
Armstrong DW, Demond W, Alak A, Anal. Chem., 57, 234 (1985)
Forgacs E, Cserhati T, "Molecular Basis of Chromatographic Separation," CRC Press LLC, New York, 122 (1997)
Janson JC, Korean J. Chem. Eng., 18(2), 149 (2001)
Kim YD, Lee JK, Cho YS, Korean J. Chem. Eng., 18(6), 971 (2001)
Krieg HM, Breytenbach JC, Keizer K, J. Membr. Sci., 164(1-2), 177 (2000)
Lee CH, J. Appl. Polym. Sci., 26, 489 (1981)
Miyata T, Iwamoto T, Uragami T, J. Appl. Polym. Sci., 51, 2007 (1986)
Moon JK, Keum DK, Lee WK, Korean J. Chem. Eng., 6(3), 172 (1989)
Sreenivasan K, J. Appl. Polym. Sci., 60(12), 2245 (1996)
Sreenivasan K, J. Appl. Polym. Sci., 70(1), 15 (1998)
Szejtli J, Chem. Rev., 98(5), 1743 (1998)
Zhao XB, He BL, React. Polym., 24(1), 1 (1994)
