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Received January 2, 2006
Accepted June 12, 2006
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Kinetics of volume expansion during infusion of Ringer’s solution based on two volume model
Dept. of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan, Seoul 138-736, Korea 1Dept. of Chemical Engineering, Hanyang University, Seoul 133-791, Korea
Korean Journal of Chemical Engineering, November 2006, 23(6), 867-873(7), 10.1007/s11814-006-0001-7
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Abstract
In this work mathematical models were developed to represent the kinetics of volume changes of fluid spaces associated with infusion of Ringer’s solution. During infusion of Ringer’s solution, the human body is assumed to be characterized by the two-fluid space model which has second volume space in addition to the first volume so that fluid exchanges between these two spaces are possible. Various infusion types were tested to accommodate different medical situations. Volunteers were given Ringer’s solution and the changes in blood hemoglobin were detected. From the comparison with experimental data, the two-fluid space model was found to represent adequately the kinetics of human volume expansion during infusion of Ringer’s solution.
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Svensen C, Hahn RG, Anesthesiology, 87, 204 (1997)
