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Conflict of Interest: In relation to this article, we declare that there is no conflict of interest.

Publication history: Received August 6, 2008
Accepted September 18, 2008

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Preparation of D-phenylalanine imprinted microbeads by the modified suspension polymerization using a magnetic impeller

Jae Seung Lee Joong Kon Park^†

Department of Chemical Engineering, Kyungpook National University, Daegu 702-701, Korea

parkjk@knu.ac.kr

Korean Journal of Chemical Engineering, March 2009, 26(2), 453-456(4), 10.1007/s11814-009-0077-y

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Abstract

Molecularly imprinted polymeric microbeads (MIPMs) were prepared by using a magnetic impeller by the modified suspension polymerization method with D-phenylalanine (Phe) as the water-soluble template without derivatization, methacrylic acid as the functional monomer, ethylene glycol dimethacrylate as the cross-linker, toluene as the porogen, polyvinyl alcohol as the stabilizer, and sodium dodecyl sulfate as the surfactant. The mean diameter of MIPMs decreased from 12.45 μm to 8.86 μm by using a simple magnetic impeller instead of a conventional simple straight-blade turbine impeller during suspension polymerization. The adsorption selectivity of MIPMs prepared with a magnetic impeller was much improved as compared to the adsorption selectivity of MIPMs prepared with a conventional simple straight-blade turbine impeller. The adsorption selectivity of MIPMs changed from reversed adsorption_x000D_ (less than 1) to positive (higher than 1) as the washing time increased after suspension polymerization.

Keywords

Molecularly Imprinted Polymeric Microbead Phenylalanine Modified Suspension Polymerization Enantioselective Separation Molecular Recognition Impeller

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