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In relation to this article, we declare that there is no conflict of interest.
Publication history
Received May 22, 2009
Accepted June 24, 2009
articles This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Dependence of approaching velocity on the force-distance curve in AFM analysis

Department of Chemical Engineering, Kwangwoon University, Seoul 139-701, Korea 1School of Chemical & Biological Engineering, Seoul National University, Seoul 151-742, Korea
korea1@kw.ac.kr
Korean Journal of Chemical Engineering, January 2010, 27(1), 324-327(4), 10.1007/s11814-009-0314-4
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Abstract

The force-distance (F-D) curve in AFM analysis is a useful technique in the field of biophysics and surface science for measuring the physical/chemical properties of a substrate. Herein, the dependence of Vz on the F-D curve has been described via a theoretical investigation confirmed with measured data. The results show the attractive force was gradually reduced above a Vz of 5 μm/s by increasing the external repulsive force loaded onto the cantilever. To obtain a non-distorted F-D curve, one of two methods should be used: to analyze F-D curve under Vz of 1 μm/s or use of a short/stiff cantilever.

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