Articles & Issues
- Language
- English
- Conflict of Interest
- In relation to this article, we declare that there is no conflict of interest.
- Publication history
-
Received July 31, 2009
Accepted November 18, 2009
-
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits
unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © KIChE. All rights reserved.
All issues
Mixing parameters for an airlift bioreactor considering constant cross sectional area of riser to downcomer: Effect of sparging gas location
Department of Chemical Engineering, Faculty of Engineering, Razi University, Kermanshah, Iran
Behin@razi.ac.ir
Korean Journal of Chemical Engineering, July 2010, 27(4), 1226-1232(7), 10.1007/s11814-010-0184-9
Download PDF
Abstract
The effect of mode of sparging gas on the mixing parameters of an internal loop airlift bioreactor was investigated. Two bioreactors of identical volume of 14×10^(3) cm^(3) and the optimum riser to downcomer cross sectional area ratio of 0.6 were studied. In one bioreactor a gas sparger was located in the draft tube and in the annulus in another. Liquid mixing characteristics, i.e., mixing time and circulation time, were employed to describe the performance of the bioreactors. The tracer injection method was used to determine the mixing parameters. A mathematical modeling_x000D_
based on the tanks-in-series model was employed to characterize the hydrodynamics behavior of the bioreactors. Matlab 7.1 software was used to solve the model equations in the Laplace domain and determine the model parameter, the number of stages. A comparison between the simulation results and experimental data showed that the applied model can accurately describe the behavior of the bioreactors. The results showed that when the gas sparger was located in_x000D_
the draft tube, the liquid mixing time, circulation time, and the number of stage were less than while the gas sparger was located in annulus. This is due to more wall effects, more energy losses and pressure drop in the case of gas injection in the annulus.
Keywords
References
Jajuee B, Margaritis A, Karamanev D, Bergougnou MA, Chem. Eng. J., 125(2), 119 (2006)
Wang PM, Huang TK, Cheng HP, Chien YH, Wu WT, J. Chem. Eng. Jpn., 35(4), 354 (2002)
Zhang P, Yang M, Lu XP, Chin. J. Chem. Eng., 15(2), 196 (2007)
Song HJ, Li H, Seo JH, Kim MJ, Kim SJ, Korean J. Chem. Eng., 26(1), 141 (2009)
Lee KB, Chun BH, Lee JC, Park CJ, Kim SH, Korean J. Chem. Eng., 19(1), 87 (2002)
Kim DJ, Ahn DH, Lee DI, Korean J. Chem. Eng., 22(1), 85 (2005)
Muthukumar K, Velan M, J. Chem. Eng. Jpn., 38(4), 253 (2005)
Lin TJ, Chen PC, J. Chem. Eng., 40, 69 (2005)
Park CJ, Korean J. Chem. Eng., 16(5), 694 (1999)
Zhang T, Wang J, Luo Z, Jin Y, J. Chem. Eng., 109, 115 (2005)
Freitas C, Teixeira JA, Bioprocess. Eng., 18, 267 (1998)
Fadavi A, Chisti Y, Chem. Eng. J., 131(1-3), 105 (2007)
Bando Y, Hayakawa H, Nishimura M, J. Chem. Eng. Jpn., 31(5), 765 (1998)
Pollard DJ, Ayazi Shamlou P, Lilly MD, Ison MP, Bioproc.Biosystems Eng. J., 15, 279 (1996)
Koide K, Horib K, Kitaguchi H, Suzuki N, J. Chem. Eng.Japan., 17, 547 (1984)
Weiland P, Ger. Chem. Eng., 7, 374 (1984)
Gavrilescu M, Tudose RZ, Chem. Eng. Process., 38(3), 225 (1999)
Levenspiel O, Chem. React. Eng., 3rd Ed., John Wiley & Sons, New York,295 (1999)
Znad H, Bales V, Markos J, Kawase Y, Biochem. Eng. J., 21, 73 (2004)
Prokop A, Erickson LE, Fernandez J, Humphrey AE, Biotechnol.Bioeng., 11, 945 (1969)
Erickson LE, Lee SS, Fan LT, J. Appl. Chem. Biotechnol., 22, 199 (1972)
Turner JR, Mills PL, Chem. Eng. Sci., 45, 2317 (1990)
Kanai T, Uzumaki T, Kawase Y, Comput. Chem. Eng., 20(9), 1089 (1996)
Choi KH, Korean J. Chem. Eng., 16(4), 441 (1999)
Varedi Kolaei M, Karimzadeh R, Shojaosadati SA, Towfighi J, Iranian. J. Biotechnol., 5, 87 (2007)
Sikula I, Jurascik M, Markos J, Chem. Eng. Sci., 62(18-20), 5216 (2007)
Blazej A, Kisa A, Markos J, Chem. Eng. Process., 43(12), 1519 (2004)
Wang PM, Huang TK, Cheng HP, Chien YH, Wu WT, J. Chem. Eng. Jpn., 35(4), 354 (2002)
Zhang P, Yang M, Lu XP, Chin. J. Chem. Eng., 15(2), 196 (2007)
Song HJ, Li H, Seo JH, Kim MJ, Kim SJ, Korean J. Chem. Eng., 26(1), 141 (2009)
Lee KB, Chun BH, Lee JC, Park CJ, Kim SH, Korean J. Chem. Eng., 19(1), 87 (2002)
Kim DJ, Ahn DH, Lee DI, Korean J. Chem. Eng., 22(1), 85 (2005)
Muthukumar K, Velan M, J. Chem. Eng. Jpn., 38(4), 253 (2005)
Lin TJ, Chen PC, J. Chem. Eng., 40, 69 (2005)
Park CJ, Korean J. Chem. Eng., 16(5), 694 (1999)
Zhang T, Wang J, Luo Z, Jin Y, J. Chem. Eng., 109, 115 (2005)
Freitas C, Teixeira JA, Bioprocess. Eng., 18, 267 (1998)
Fadavi A, Chisti Y, Chem. Eng. J., 131(1-3), 105 (2007)
Bando Y, Hayakawa H, Nishimura M, J. Chem. Eng. Jpn., 31(5), 765 (1998)
Pollard DJ, Ayazi Shamlou P, Lilly MD, Ison MP, Bioproc.Biosystems Eng. J., 15, 279 (1996)
Koide K, Horib K, Kitaguchi H, Suzuki N, J. Chem. Eng.Japan., 17, 547 (1984)
Weiland P, Ger. Chem. Eng., 7, 374 (1984)
Gavrilescu M, Tudose RZ, Chem. Eng. Process., 38(3), 225 (1999)
Levenspiel O, Chem. React. Eng., 3rd Ed., John Wiley & Sons, New York,295 (1999)
Znad H, Bales V, Markos J, Kawase Y, Biochem. Eng. J., 21, 73 (2004)
Prokop A, Erickson LE, Fernandez J, Humphrey AE, Biotechnol.Bioeng., 11, 945 (1969)
Erickson LE, Lee SS, Fan LT, J. Appl. Chem. Biotechnol., 22, 199 (1972)
Turner JR, Mills PL, Chem. Eng. Sci., 45, 2317 (1990)
Kanai T, Uzumaki T, Kawase Y, Comput. Chem. Eng., 20(9), 1089 (1996)
Choi KH, Korean J. Chem. Eng., 16(4), 441 (1999)
Varedi Kolaei M, Karimzadeh R, Shojaosadati SA, Towfighi J, Iranian. J. Biotechnol., 5, 87 (2007)
Sikula I, Jurascik M, Markos J, Chem. Eng. Sci., 62(18-20), 5216 (2007)
Blazej A, Kisa A, Markos J, Chem. Eng. Process., 43(12), 1519 (2004)
