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Conflict of Interest: In relation to this article, we declare that there is no conflict of interest.

Publication history: Received September 23, 2011
Accepted February 15, 2012

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Poly(vinyl alcohol) hollow microcapsules prepared by emulsification, salting out, and photo cross-linking method

Mi Sun Lee Eun Young Mok Won Cheol Shin¹ Jong Dai Kim² Jin-Chul Kim^†

Division of Biotechnology & Bioengineering and Institute of Bioscience and Biotechnology, Kangwon National University, 192-1, Hyoja-2dong, Chuncheon, Kangwon-do 200-701, Korea ¹Dapartment of Bioengineering and Technology, Kangwon National University, 192-1, Hyoja-2dong, Chuncheon, Kangwon-do 200-701, Korea ²Division of Food Biotechnology, School of Biotechnology, Kangwon National University, 192-1, Hyoja-2dong, Chuncheon, Kangwon-do 200-701, Korea

jinkim@kangwon.ac.kr

Korean Journal of Chemical Engineering, August 2012, 29(8), 1108-1113(6), 10.1007/s11814-012-0020-5

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Abstract

Coumarin residues were conjugated to poly(vinyl alcohol) (PVA) by reacting epoxypropoxy coumarin (EPC) with the polymer. According to the peak areas on the 1H NMR spectrum, EPC was calculated to be conjugated to every 283 repeating units (vinyl alcohols). A cyclic photo-dimerization and dedimerization of EPC of PVA-EPC conjugate were observed under a cyclic irradiation of 365 nm and 254 nm. The salting-out of the conjugate significantly took a place in the range of 0-2.0M NaCl, and the phenomenon was observed at a lower concentration than that of_x000D_ unmodified PVA was. Oil-in-water emulsion was prepared as a template for the preparation of hollow microcapsules using chloroform as an oil phase and PVA-EPC as an emulsifier. The emulsion was stable for 24 hr in terms of droplet size. The wall surrounding droplets was built-up by the salting-out of PVA-EPC, and it was cross-linked by the irradiation of 365 nm. After chloroform was evaporated and salt was removed by a dialysis, hollow microcapsules were successfully obtained.

Keywords

Poly(vinyl alcohol) Coumarin Salting-out Emulsion Photo-crosslinking Hollow Microcapsules

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