Articles & Issues
- Language
- English
- Conflict of Interest
- In relation to this article, we declare that there is no conflict of interest.
- Publication history
-
Received August 18, 2015
Accepted October 17, 2015
- This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © KIChE. All rights reserved.
All issues
Combined operation of outlet streams swing with partial-feed in a simulated moving bed
Department of Chemical and Biomolecular Engineering, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Korean Journal of Chemical Engineering, March 2016, 33(3), 1059-1069(11), 10.1007/s11814-015-0220-x
Download PDF
Abstract
The operational strategy of outlet streams swing (OSS) operation combined with partial-feed (PF) operation, OSS-PF, was studied under the constraint of maximum allowable pressure and flow-rate. Its separation performance and dynamic behavior were compared with those of OSS operation and conventional simulated moving bed (SMB) chromatography. During OSS-PF operation, the switching period consisted of two steps; raffinate was produced during the closed condition of extract node and feed node in the first step, while extracts were produced and feeds were injected during the closed condition of raffinate node in the second step. As a result, OSS-PF operation could be performed under the allowable maximum flow-rate in the corresponding conventional SMB without generating an additional pressure drop at the adsorbent bed, which was different from OSS operation. OSS-PF operation successfully improved the separation performance of the conventional SMB with regard to extract purity, raffinate recovery and raffinate productivity with equivalent eluent consumption. The step ratio during a switching period worked as one of important operating variables in separation performance. The dynamic behavior of OSS-PF operation was analyzed and compared with that of OSS and conventional SMB using simulated concentration profiles in the fluid phase.
References
Johnson JA, Kabza RG, in Ganetsos G, Barker PE (Editors), Preparative and Production Scale Chromatography, Marcel Dekker, New York (1993).
Long NVD, Lee JW, Le TH, Kim JI, Koo YM, J. Chem. Eng., 28, 1110 (2011)
Lee J, Shin NC, Lim Y, Han C, Korean J. Chem. Eng., 27(2), 609 (2010)
Rajendran A, Paredes G, Mazzotti M, J. Chromatogr. A, 1216, 709 (2009)
Schulte M, Strube J, J. Chromatogr. A, 906, 399 (2001)
Lee E, Park MB, Kim JM, Kim WS, Kim IH, Korean J. Chem. Eng., 27(1), 231 (2010)
Bae YS, Lee CH, J. Chromatogr. A, 1122, 161 (2006)
Kim KM, Lee HH, Lee CH, Ind. Eng. Chem. Res., 51(29), 9835 (2012)
Schramm H, Kienle A, Kaspereit M, Seidel-Morgenstern A, Chem. Eng. Sci., 58(23-24), 5217 (2003)
Kim KM, Lee CH, J. Chromatogr. A, 1311, 79 (2013)
Lee HH, Kim KM, Lee CH, AIChE J., 57(8), 2036 (2011)
Zang YF, Wankat PC, Ind. Eng. Chem. Res., 41(10), 2504 (2002)
Kim JK, Abunasser N, Wankat PC, Korean J. Chem. Eng., 22(4), 619 (2005)
Gomes PS, Rodrigues AE, Sep. Sci. Technol., 42(2), 223 (2007)
Kim KM, Song JY, Lee CH, J. Chromatogr. A, 1340, 79 (2014)
Mun S, Ind. Eng. Chem. Res., 49(19), 9258 (2010)
Mun S, J. Chromatogr. A, 1218, 8060 (2011)
Sreedhar B, Kawajiri Y, Chem. Eng. Sci., 116, 428 (2014)
Song JY, Oh D, Lee CH, J. Chromatogr. A, 1403, 205 (2015)
Mazzotti M, Storti G, Morbidelli M, J. Chromatogr. A, 769, 3 (1997)
Guiochon G, Shirazi SG, Katti AM, Fundamentals of Preparative and Nonlinear Chromatography, Elsevier Academic Press, Boston, MA, 2nd Ed. (1994).
Gomes PS, Rodrigues AE, Sep. Sci. Technol., 45(16), 2259 (2010)
Lee KB, Chin CY, Xie Y, Cox GB, Wang NHL, Ind. Eng. Chem. Res., 44(9), 3249 (2005)
Ergun S, Chem. Eng. Prog., 48, 89 (1952)
Charton F, Nicoud RM, J. Chromatogr. A, 702, 97 (1995)
Long NVD, Lee JW, Le TH, Kim JI, Koo YM, J. Chem. Eng., 28, 1110 (2011)
Lee J, Shin NC, Lim Y, Han C, Korean J. Chem. Eng., 27(2), 609 (2010)
Rajendran A, Paredes G, Mazzotti M, J. Chromatogr. A, 1216, 709 (2009)
Schulte M, Strube J, J. Chromatogr. A, 906, 399 (2001)
Lee E, Park MB, Kim JM, Kim WS, Kim IH, Korean J. Chem. Eng., 27(1), 231 (2010)
Bae YS, Lee CH, J. Chromatogr. A, 1122, 161 (2006)
Kim KM, Lee HH, Lee CH, Ind. Eng. Chem. Res., 51(29), 9835 (2012)
Schramm H, Kienle A, Kaspereit M, Seidel-Morgenstern A, Chem. Eng. Sci., 58(23-24), 5217 (2003)
Kim KM, Lee CH, J. Chromatogr. A, 1311, 79 (2013)
Lee HH, Kim KM, Lee CH, AIChE J., 57(8), 2036 (2011)
Zang YF, Wankat PC, Ind. Eng. Chem. Res., 41(10), 2504 (2002)
Kim JK, Abunasser N, Wankat PC, Korean J. Chem. Eng., 22(4), 619 (2005)
Gomes PS, Rodrigues AE, Sep. Sci. Technol., 42(2), 223 (2007)
Kim KM, Song JY, Lee CH, J. Chromatogr. A, 1340, 79 (2014)
Mun S, Ind. Eng. Chem. Res., 49(19), 9258 (2010)
Mun S, J. Chromatogr. A, 1218, 8060 (2011)
Sreedhar B, Kawajiri Y, Chem. Eng. Sci., 116, 428 (2014)
Song JY, Oh D, Lee CH, J. Chromatogr. A, 1403, 205 (2015)
Mazzotti M, Storti G, Morbidelli M, J. Chromatogr. A, 769, 3 (1997)
Guiochon G, Shirazi SG, Katti AM, Fundamentals of Preparative and Nonlinear Chromatography, Elsevier Academic Press, Boston, MA, 2nd Ed. (1994).
Gomes PS, Rodrigues AE, Sep. Sci. Technol., 45(16), 2259 (2010)
Lee KB, Chin CY, Xie Y, Cox GB, Wang NHL, Ind. Eng. Chem. Res., 44(9), 3249 (2005)
Ergun S, Chem. Eng. Prog., 48, 89 (1952)
Charton F, Nicoud RM, J. Chromatogr. A, 702, 97 (1995)