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Received May 29, 2015
Accepted September 30, 2015
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The antimicrobial activity of as-prepared silver-loaded phosphate glasses and zirconium phosphate
State Key Laboratory of Green Building Materials, China Building Materials Academy, Beijing 100024, China 1Department of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China
wangcbma@263.net
Korean Journal of Chemical Engineering, March 2016, 33(3), 952-957(6), 10.1007/s11814-015-0207-7
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Abstract
The antimicrobial activities of silver-loaded zirconium phosphate (JDG) and silver-loaded phosphate glasses (ZZB) against Escherichia coli were studied. Although the silver content in JDG was higher than that in ZZB, ZZB suspensions showed better antimicrobial property than JDG suspensions, especially at low concentrations. The antimicrobial activity was analyzed using minimum inhibitory concentrations, bacterial inhibition ring tests, and detection of silver ions in the suspensions. Furthermore, the amounts of silver ions in suspensions with/without bacterial cells were analyzed. Results revealed that only a portion of released silver ions could be adsorbed by E. coli cells, which are critical to cell death. The damaged microstructures of E. coli cells observed by transmission electron microscopy may further prove that the adsorbed silver ions play an important role in the antimicrobial process.
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References
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Wang JX, Wen LX, Wang ZH, Chen JF, Mater. Chem. Phys., 96(1), 90 (2006)