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Received June 5, 2019
Accepted September 24, 2019
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Design and bio-applications of biological metal-organic frameworks
State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin University of Science and Technology, No 29 13th, Avenue, Tianjin Economic and Technological Development Area (TEDA), Tianjin 300457, P. R. China 1School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China 2Bristol Dental School, University of Bristol, Bristol BS1 2LY, United Kingdom, UK
jiashiru@tust.edu.cn
Korean Journal of Chemical Engineering, December 2019, 36(12), 1949-1964(16), 10.1007/s11814-019-0394-8
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Abstract
Biological metal-organic frameworks (bioMOFs) are a new subclass of the MOF family. In comparison with traditional MOFs, the bioMOFs are made of multifunctional biologically related ligands (bio-ligand) and metal ions. The bio-ligands confer biological compatibility for traditional MOFs, thus providing many opportunities for a wide array of biological applications. This review highlights the recent advances in the synthesis of bioMOFs comprising multifunctional bio-ligands and metal ions. These bio-ligands include nucleobases, amino acids, peptides, proteins, cyclodextrin, saccharides, and other biomolecules. Furthermore, the potential bio-applications of bioMOFs in several fields such as biomedicine, biosensing and bioimaging, antimicrobial applications, biomimetic catalysis, chiral separation, and environmental protection are also demonstrated.
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