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Received July 12, 2022
Accepted September 8, 2022
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This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits
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Fabrication and application of drug eluting stent for peripheral artery disease
1Interventional Therapy R & D center, M.I.Tech Co., Ltd, Pyeongtaek-si, Gyeonggi-do 17706, Korea 2Department of Organic Materials Engineering, Chungnam National University, Daejeon 34134, Korea 3Department of Nature-Inspired Nanoconvergence Systems, Korea Institute of Machinery and Materials, Daejeon 34103, Korea
psa@kimm.re.kr
Korean Journal of Chemical Engineering, February 2023, 40(2), 361-368(8), 10.1007/s11814-022-1286-x
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Abstract
The stenosis of peripheral arteries, including the superficial femoral artery (SFA), can be addressed by a minimally invasive procedure involving a self-expandable metallic stent (SEMS). These SEMSs are commonly laser-cut types comprising nickel-titanium alloys. However, laser-cut SEMS can be fractured by the multiple biomechanical stresses occurring in the SFA, owing to their limited flexibility and susceptibility to permanent deformation under external pressure. To reduce the incidence of stent fracture in the SFA lesion, in this study, new interwoven stent designs were developed using a nickel-titanium alloy with double-helical sutures of poly(glycolic acid) (PGA). To achieve long term patency and prevent restenosis of the inserted SEMS, a drug eluting stent was fabricated for peripheral artery disease as new manufacturing concept (and contrasted with an identical bare metal stent (BMS) control), and the safety and efficacy of this fabricated stent were demonstrated through an in vivo test.
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References
Hirsch AT, Criqui MH, Treat-Jacobson D, Regensteiner JG, Creager MA, Olin JW, Krook SH, Hunninghake DB, JAMA, 286, 1317 (2001)
Scheinert D, Scheinert S, Sax J, Piorkowski C, Bräunlich S, Ulrich M, Biamino G, Schmidt A, J. Am. Coll. Cardiol., 45, 312 (2005)
Rits J, van Herwaarden JA, Jahrome AK, Krievinsa D, Mollb FL, Eur. J. Vasc. Endovasc. Surg., 36, 339 (2008)
Adlakha S, Sheikh M, Wu J, Burket MW, Pandya U, Colyer W, Eltahawy E, Cooper CJ, J. Interv. Cardiol., 23, 411 (2010)
Lida O, Nanto S, Uematsu M, Morozumi T, Kotani J, Awata M, Onishi T, Ito N, Sera F, Minamiguchi H, Akahori H, Nagata S, Am. J. Cardiol., 98, 272 (2006)
Davaine JM, Azema L, Guyomarch B, Chaillou P, Costargent A, Patra P, Lambert G, Gouëffic Y, Eur. J. Vasc. Endovasc. Surg., 44, 432 (2012)
Bosiers M, Deloose K, Callaert J, Moreels N, Keirse K, Verbist J, Peeters P, J. Vasc. Surg., 54, 1042 (2011)
Bosiers M, Torsello G, Gissler HM, Ruef J, Müller-Hülsbeck S, Jahnke T, Peeters P, Daenens K, Lammer J, Schroë H, J. Endovasc. Ther., 16, 261 (2009)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, Mudde C, J. Endovasc. Ther., 13, 701 (2006)
Schillinger M, Sabeti S, Loewe C, Dick P, Amighi J, Mlekusch W, Schlager O, Cejna M, Lammer J, Minar E, N. Engl. J. Med., 354, 1879 (2006)
Krankenberg H, Schluter M, Steinkamp HJ, Bürgelin K, Scheinert D, Schulte KL, Minar E, Peeters P, Bosiers M, Circulation, 116, 285 (2007)
Laird JR, Katzen BT, Scheinert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Circ. Cardiovasc. Interv., 3, 267 (2010)
Werner M, Paetzold A, Banning-Eichenseer U, Scheinert S, Piorkowski M, Ulrich M, Bausback Y, Bräunlich S, Schmidt A, EuroIntervention, 10, 861 (2014)
Scheinert D, Grummt L, Piorkowski M, Sax J, Scheinert S, Ulrich M, Werner M, Bausback Y, Braunlich S, Schmidt A, J. Endovasc. Ther., 18, 745 (2011)
Scheinert D, Werner M, Scheinert S, Paetzold A, Banning-Eichenseer U, Piorkowski M, Ulrich M, Bausback Y, Bräunlich S, JACC Cardiovasc. Interv., 6, 65 (2013)
Werner M, Piorkowski M, Thieme M, Nanning T, Beschorner U, Rastan A, Zeller T, Scheinert D, J. Endovasc. Ther., 20, 759 (2013)
Rosenfield K, Jaff MR, White CJ, Rocha-Singh K, Mena-Hurtado C, Metzger DC, Brodmann M, Pilger E, Zeller T, Krishnan P, N. Engl. J. Med., 373, 145 (2015)
Laird JR, Schneider PA, Tepe G, Brodmann M, Zeller T, Metzger C, Krishnan P, Scheinert D, Micari A, Cohen DJ, Wang H, J. Am. Coll. Cardiol., 66, 2329 (2015)
Sarode K, Spelber DA, Bhatt DL, Mohammad A, Prasad A, Brilakis ES, Banerjee S, JACC Cardiovasc. Interv., 7, 827 (2014)
Acharya G, Park K, Adv. Drug Deliv. Rev., 58, 387 (2006)
Kang E, Vedantham K, Long X, Dadara M, Kwon IK, Sturek M, Park K, Mol. Pharm., 6, 1110 (2009)
Chen MC, Liang HF, Chiu YL, Chang Y, Wei HJ, Sung HW, J. Control. Release, 108, 178 (2005)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Mudde C, J. Vasc. Interv. Radiol., 16, 331 (2005)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, J. Endovasc. Ther., 13, 701 (2006)
Krankenberg H, Schluter M, Steinkamp HJ, Bürgelin K, Scheinert D, Schulte KL, Minar E, Peeters P, Bosiers M, Tepe G, Circulation, 116, 285 (2007)
Zeller T, Tiefenbacher C, Steinkamp HJ, Langhoff R, Wittenberg G, Schlüter M, Buergelin K, Rastan A, Krumsdorf U, J. Endovasc. Ther., 15, 390 (2008)
Dake MD, Scheinert D, Tepe G, Tessarek J, Fanelli F, Bosiers M, Ruhlmann C, Kavteladze Z, Lottes AE, Ragheb AO, J. Endovasc. Ther., 18, 613 (2011)
Stern JR, Tran K, Vascular., 29, 477 (2021)
Dake MD, Ansel GM, Jaff MR, Ohki T, Saxon RR, Smouse HB, Zeller T, Roubin GS, Burket MW, Khatib Y, Snyder SA, Circ. Cardiovasc. Interv., 4, 495 (2011)
Laird JR, Katzen BT, Schienert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Circ. Cardiovasc. Interv., 3, 267 (2010)
Dake MD, Ansel GM, Jaff MR, Ohki T, Saxon RR, Smouse HB, Machan LS, Snyder SA, O’Leary EE, Ragheb AO, Circulation, 133, 1472 (2016)
McDermott MM, Kibbe MR, Nat. Rev. Cardiol., 18, 311 (2021)
Mohammed H, Azhar A, Syeda T, EJMCM, 9, 3588 (2020)
Walker JP, Owens CD, Curr. Surg. Rep., 1, 90 (2013)
Rodés J, Côté G, Lespérance J, Bourassa MG, Doucet S, Bilodeau L, Bertrand OF, Harel F, Gallo R, Tardif JC, Circulation, 97, 429 (1998)
Chen Y, Gao P, Huang L, Tan X, Zhou N, Yang T, Qiu H, Dai X, Michael S, Tu Q, Huang N, Guo Z, Zhou J, Yang Z, Nat. Commun., 12, 7079 (2021)
Allie D, Herbert C, Walker C, Endovasc. Today, 6, 22 (2004)
Berry JL, Manoach E, Mekkaoui C, J. Vasc. Interv. Radiol., 13, 97 (2002)
Rachev A, Manoach E, Berry J, Moore JE, J. Theor. Biol., 206, 429 (2000)
Jang BS, Jeong JE, Ji S, Im D, Lee MK, Park SA, Park WH, Mater. Des., 195, 109005 (2020)
Altit R, Gray WA, Curr. Cardiol. Rep., 19, 117 (2017)
Elens M, Verhelst R, Possoz J, Mastrobuoni S, Lacroix V, Astarci P, Surg. Technol. Int., 31, 162 (2017)
Goueffic Y, Kaladji A, Guyomarch B, Montagne C, Fairier D, Gestin S, Riche VP, Vent PA, Chaillou P, Costargent A, Patra P, Trials, 15, 423 (2014)
Lee JH, Kim SJ, Park SI, Ko YG, Choi D, Hong MK, Jang Y, Biomed. Res. Int., 6915789 (2016)
Litsky J, Chanda A, Stilp E, Lansky A, Mena C, Med. Devices, 7, 149 (2014)
Ogawa Y, Yokoi H, Ohki T, Kichikawa K, Nakamura M, Komori K, Nanto S, O’Leary EE, Lottes AE, Saunders AT, Dake MD, Cardiovasc. Intervent. Radiol., 40, 1669 (2017)
Vent PA, Kaladji A, Davaine JM, Guyomarch B, Chaillou P, Costargent A, Quillard T, Goueffic Y, Ann. Vasc. Surg., 43, 166 (2017)
Scheinert D, Scheinert S, Sax J, Piorkowski C, Bräunlich S, Ulrich M, Biamino G, Schmidt A, J. Am. Coll. Cardiol., 45, 312 (2005)
Rits J, van Herwaarden JA, Jahrome AK, Krievinsa D, Mollb FL, Eur. J. Vasc. Endovasc. Surg., 36, 339 (2008)
Adlakha S, Sheikh M, Wu J, Burket MW, Pandya U, Colyer W, Eltahawy E, Cooper CJ, J. Interv. Cardiol., 23, 411 (2010)
Lida O, Nanto S, Uematsu M, Morozumi T, Kotani J, Awata M, Onishi T, Ito N, Sera F, Minamiguchi H, Akahori H, Nagata S, Am. J. Cardiol., 98, 272 (2006)
Davaine JM, Azema L, Guyomarch B, Chaillou P, Costargent A, Patra P, Lambert G, Gouëffic Y, Eur. J. Vasc. Endovasc. Surg., 44, 432 (2012)
Bosiers M, Deloose K, Callaert J, Moreels N, Keirse K, Verbist J, Peeters P, J. Vasc. Surg., 54, 1042 (2011)
Bosiers M, Torsello G, Gissler HM, Ruef J, Müller-Hülsbeck S, Jahnke T, Peeters P, Daenens K, Lammer J, Schroë H, J. Endovasc. Ther., 16, 261 (2009)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, Mudde C, J. Endovasc. Ther., 13, 701 (2006)
Schillinger M, Sabeti S, Loewe C, Dick P, Amighi J, Mlekusch W, Schlager O, Cejna M, Lammer J, Minar E, N. Engl. J. Med., 354, 1879 (2006)
Krankenberg H, Schluter M, Steinkamp HJ, Bürgelin K, Scheinert D, Schulte KL, Minar E, Peeters P, Bosiers M, Circulation, 116, 285 (2007)
Laird JR, Katzen BT, Scheinert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Circ. Cardiovasc. Interv., 3, 267 (2010)
Werner M, Paetzold A, Banning-Eichenseer U, Scheinert S, Piorkowski M, Ulrich M, Bausback Y, Bräunlich S, Schmidt A, EuroIntervention, 10, 861 (2014)
Scheinert D, Grummt L, Piorkowski M, Sax J, Scheinert S, Ulrich M, Werner M, Bausback Y, Braunlich S, Schmidt A, J. Endovasc. Ther., 18, 745 (2011)
Scheinert D, Werner M, Scheinert S, Paetzold A, Banning-Eichenseer U, Piorkowski M, Ulrich M, Bausback Y, Bräunlich S, JACC Cardiovasc. Interv., 6, 65 (2013)
Werner M, Piorkowski M, Thieme M, Nanning T, Beschorner U, Rastan A, Zeller T, Scheinert D, J. Endovasc. Ther., 20, 759 (2013)
Rosenfield K, Jaff MR, White CJ, Rocha-Singh K, Mena-Hurtado C, Metzger DC, Brodmann M, Pilger E, Zeller T, Krishnan P, N. Engl. J. Med., 373, 145 (2015)
Laird JR, Schneider PA, Tepe G, Brodmann M, Zeller T, Metzger C, Krishnan P, Scheinert D, Micari A, Cohen DJ, Wang H, J. Am. Coll. Cardiol., 66, 2329 (2015)
Sarode K, Spelber DA, Bhatt DL, Mohammad A, Prasad A, Brilakis ES, Banerjee S, JACC Cardiovasc. Interv., 7, 827 (2014)
Acharya G, Park K, Adv. Drug Deliv. Rev., 58, 387 (2006)
Kang E, Vedantham K, Long X, Dadara M, Kwon IK, Sturek M, Park K, Mol. Pharm., 6, 1110 (2009)
Chen MC, Liang HF, Chiu YL, Chang Y, Wei HJ, Sung HW, J. Control. Release, 108, 178 (2005)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Mudde C, J. Vasc. Interv. Radiol., 16, 331 (2005)
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, J. Endovasc. Ther., 13, 701 (2006)
Krankenberg H, Schluter M, Steinkamp HJ, Bürgelin K, Scheinert D, Schulte KL, Minar E, Peeters P, Bosiers M, Tepe G, Circulation, 116, 285 (2007)
Zeller T, Tiefenbacher C, Steinkamp HJ, Langhoff R, Wittenberg G, Schlüter M, Buergelin K, Rastan A, Krumsdorf U, J. Endovasc. Ther., 15, 390 (2008)
Dake MD, Scheinert D, Tepe G, Tessarek J, Fanelli F, Bosiers M, Ruhlmann C, Kavteladze Z, Lottes AE, Ragheb AO, J. Endovasc. Ther., 18, 613 (2011)
Stern JR, Tran K, Vascular., 29, 477 (2021)
Dake MD, Ansel GM, Jaff MR, Ohki T, Saxon RR, Smouse HB, Zeller T, Roubin GS, Burket MW, Khatib Y, Snyder SA, Circ. Cardiovasc. Interv., 4, 495 (2011)
Laird JR, Katzen BT, Schienert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Circ. Cardiovasc. Interv., 3, 267 (2010)
Dake MD, Ansel GM, Jaff MR, Ohki T, Saxon RR, Smouse HB, Machan LS, Snyder SA, O’Leary EE, Ragheb AO, Circulation, 133, 1472 (2016)
McDermott MM, Kibbe MR, Nat. Rev. Cardiol., 18, 311 (2021)
Mohammed H, Azhar A, Syeda T, EJMCM, 9, 3588 (2020)
Walker JP, Owens CD, Curr. Surg. Rep., 1, 90 (2013)
Rodés J, Côté G, Lespérance J, Bourassa MG, Doucet S, Bilodeau L, Bertrand OF, Harel F, Gallo R, Tardif JC, Circulation, 97, 429 (1998)
Chen Y, Gao P, Huang L, Tan X, Zhou N, Yang T, Qiu H, Dai X, Michael S, Tu Q, Huang N, Guo Z, Zhou J, Yang Z, Nat. Commun., 12, 7079 (2021)
Allie D, Herbert C, Walker C, Endovasc. Today, 6, 22 (2004)
Berry JL, Manoach E, Mekkaoui C, J. Vasc. Interv. Radiol., 13, 97 (2002)
Rachev A, Manoach E, Berry J, Moore JE, J. Theor. Biol., 206, 429 (2000)
Jang BS, Jeong JE, Ji S, Im D, Lee MK, Park SA, Park WH, Mater. Des., 195, 109005 (2020)
Altit R, Gray WA, Curr. Cardiol. Rep., 19, 117 (2017)
Elens M, Verhelst R, Possoz J, Mastrobuoni S, Lacroix V, Astarci P, Surg. Technol. Int., 31, 162 (2017)
Goueffic Y, Kaladji A, Guyomarch B, Montagne C, Fairier D, Gestin S, Riche VP, Vent PA, Chaillou P, Costargent A, Patra P, Trials, 15, 423 (2014)
Lee JH, Kim SJ, Park SI, Ko YG, Choi D, Hong MK, Jang Y, Biomed. Res. Int., 6915789 (2016)
Litsky J, Chanda A, Stilp E, Lansky A, Mena C, Med. Devices, 7, 149 (2014)
Ogawa Y, Yokoi H, Ohki T, Kichikawa K, Nakamura M, Komori K, Nanto S, O’Leary EE, Lottes AE, Saunders AT, Dake MD, Cardiovasc. Intervent. Radiol., 40, 1669 (2017)
Vent PA, Kaladji A, Davaine JM, Guyomarch B, Chaillou P, Costargent A, Quillard T, Goueffic Y, Ann. Vasc. Surg., 43, 166 (2017)
