Azo compounds have long posed a serious threat to publish health and the aquatic environment. Therefore, the adverse eff ects

of azo compounds on public health have inspired the need to develop effi cient and reliable treatment methods. Although various

physicochemical treatment methods have been developed, bio-inspired environmentally friendly treatment method have

not yet been reported. Here, we report the development of a novel azo compound treatment method using biogenic nanoparticles

immobilized microorganism. Firstly, biogenic bimetallic iron–molybdenum nanoparticles immobilized Deinococcus

radiodurans R1 (DR-FeMoNPs) were constructed. Next, physicochemical properties of FeMoNPs including specifi c surface

area (53.627 m 2 g −1 ), pore volume (0.3561 cm 3 g −1 ), and average pore diameter (19.205 nm) were thoroughly addressed.

The resulting FeMoNPs-immobilized D. radiodurans R1 exhibited an 87.2% removal effi ciency for Congo Red, with a

maximum capacity of 172.4 mg/g. Additionally, the rapid degradation of residual H 2 O 2 , triggering Fenton-like reaction via

biological scavenging mechanism, was confi rmed. DR-FeMoNPs also demonstrated highly effi cient removal of other types

of azo compounds, such as Acid Orange 7 (99.4%) and Evans Blue (81.1%).