Overall
- Language
- English
- Conflict of Interest
- In relation to this article, we declare that there is no conflict of interest.
- Publication history
-
Received January 17, 2024
Accepted April 6, 2024
- This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Process Integration and Design of Amino Acid Purifi cation Processes for Energy Savings: An Industrial Case Study
Abstract
Energy minimization study is applied to an amino acids downstream process for L-methionine production currently in
operation and energy-saving options that can be implemented in practice are systematically identifi ed with the application
of Process Integration (PI) design method. Structural changes in process fl owsheets or reconfi guration in stream-mixing
patterns are considered for the debottlenecking of bioprocesses for energy reduction, which allows the energy-effi cient use
of steam for the purifi cation of bioproducts and its effl uent management, leading to maximum 18% saving in steam use to
be achieved. Reduction in cold utility is investigated with the strategic use of cooling water reuse, as a means of cold utility
minimization, with which up to 33% of cooling water use can be reduced. The introduction of multi-level expansion for the
provision of refrigeration utility is further identifi ed, leading to 35% reduction in compression power. The retrofi t case study
clearly demonstrates the usefulness of Process Integration method for energy minimization in bioprocesses in operation and
its results provides practical design guidelines for energy-saving projects in amino acids production.