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젖산 생산에 대한 다양한 매개변수의 영향 조사; 리뷰
Investigating the Impacts of Various Parameters on Lactic Acid Production; A Review
Hub-e-Fatima1
Hammad Zia2
Muhammad Awais3
Hafiz Miqdad Masood4
Najaf Ali5†
1NFC-Institute of Engineering & Fertilizer Research, Faisalabad Chemical Engineering, 2NFC-Institute of Engineering & Fertilizer Research, Faisalabad Chemical Engineering , 3NFC-Institute of Engineering & Fertilizer Research, Faisalabad Chemical Engineering, 4NFC-Institute of Engineering & Fertilizer Research, Faisalabad Chemical Engineering, 5NFC-Institute of Engineering & Fertilizer Research, Faisalabad Chemical Engineering
In Press, Journal Pre-proof, Available online 1 November 2024
Abstract
발효에 의한 젖산 생산은 pH, 온도, 탄소 및 질소 공급원의 선택과 같은 여러 공정 요인의 영향을 받습니다. 젖산 합성의 발달은 산성 환경에 의해 촉진되며, 일반적으로 최적의 젖산 합성이 가능한 pH < 3.5에 속합니다. 또 다른 중요한 요소는 온도입니다. Lactobacillus rhamnosus DUT1908과 같은 균주는 50°C의 높은 온도에 대한 높은 내성을 갖고 있어 효과적인 기질 활용과 높은 젖산 수율을 가능하게 합니다. 관찰된 최대 젖산 농도는 포도당 60g/l와 자당에서 21g/l였으며, 이는 두 탄소원 사이의 젖산 생산에 상당한 차이가 있음을 보여줍니다. 호열성 미생물과 효소는 공정 효율성을 높이는 능력 때문에 연구됩니다. 더욱이, 미생물의 유전공학 발전으로 인해 젖산 생산이 극적으로 증가했습니다. 이 논문은 또한 유리한 전분 분해 특성을 갖고 재생 가능한 탄소원을 대사할 수 있는 Rhizopus 종과 같은 곰팡이의 활용에 대해서도 논의합니다.
The production of lactic acid by fermentation is affected by several process factors such as, pH, temperature, selection of carbon and nitrogen sources. The development of lactic acid synthesis is promoted by acidic environment, usually falling within pH < 3.5, which allow for optimal lactic acid synthesis. Another important factor is temperature. Strains such as lactobacillus rhamnosus DUT1908, have a high tolerance to temperature as high as 50 °C, which allows foe effective substrate utilization and high lactic acid yield. The maximal lactic acid concentrations observed with glucose 60 g/l and with sucrose they were 21 g/l, demonstrating the substantial differences in lactic acid production between these two carbon sources. Thermophilic microorganisms and enzymes are investigated because of their ability to increase process efficiency. Furthermore, lactic acid production has increased dramatically as a result of genetic engineering developments in microbes. The paper also discusses the utilization of fungi, such as Rhizopus species which have advantageous amylolytic properties and can metabolize renewable carbon sources.