Articles & Issues
- Language
- korean
- Conflict of Interest
- In relation to this article, we declare that there is no conflict of interest.
- Publication history
-
Received December 22, 2006
Accepted May 22, 2007
-
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits
unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © KIChE. All rights reserved.
All issues
공침법을 이용한 은 - 수산화아파타이트 항균소재의 제조
Synthesis of Ag-Hydroxyapatite Antibiotic Material by Coprecipitation Method
서울산업대학교 화학공학과, 139-743 서울시 노원구 공릉2동 172
Department of Chemical Engineering, Seoul National University of Technology, 172, Kongneung-2-dong, Nowon-gu, Seoul 139-743, Korea
Korean Chemical Engineering Research, October 2007, 45(5), 473-478(6), NONE Epub 5 November 2007
Download PDF
Abstract
공침법을 이용하여 질산은(AgNO3)을 수산화아파타이트(hydroxyapatite)에 흡착시켜 복합항균제를 제조하였다. 질산은의 농도, 온도, 압력, 숙성시간에 따른 흡착된 은이온양의 변화를 관찰하였고, 은-수산화아파타이트 흡착의 최적조건을 얻었다. 제조된 은-수산화아파타이트를 ICP-MS, SEM-EDAX, DSC, XRD를 이용하여 물리적·화학적 특성을 고찰하였다. 또한 제조된 은-수산화아파타이트는 진탕플라스크실험법(shake flask method, KS M-146-2003)을 이용하여 양성균인 황색포도상구균(staphylococcus aureus, ATCC 6538)과 음성균인 대장균(escherichia coli, ATCC 25922)의 항균성을 확인하였다.
Antibiotic composite was synthesized by coprecipitation of silver nitrate into hydroxyapatite. Adsorbed amount of silver ion was examined by the variation of concentration of silver nitrate, temperature, pressure and curing time. Optimum condition for silver-hydroxyapatite adsorption could be achieved. Physical and chemical characteristic properties of synthesized silver-hydroxyapatite were tested by ICP-MS, SEM-EDAX, DSC and XRD. Antibiotic properties for gram positive staphylococcus aureus (ATCC 6538) and gram negative escherichia coli (ATCC 25922) were tested by shake flake method.
References
Lim YT, Choi HK, Ahn YH, Korean J. Biotechnol. Bioeng., 16(2), 123 (2001)
Tomioka Y, Miyaji T, Oka H, Tomita K, Nishino A, J. Antibact. Antifug Agents, 21(9), 503 (1993)
Shin CH, Jung SH, Park DK, J. KSEE, 19(2), 177 (1997)
Lee JI, Shin CH, Park DK, J. KSEE, 17(2), 137 (1195)
Hill WR, Pillsbury DM, the Pharmacology of Silver, The Williams & Wilkins Co., Baltimore (1973)
Davies RL, Etris SF, Catal. Today, 36(1), 107 (1997)
Cecil WC, Charles MP, Paul WK, J. AWWA, 54, 208 (1962)
Richard LW, J. AWWA, 55, 881 (1963)
Feng QL, Wu J, Chen GQ, Cui FZ, Kim JO, Biomed. Mat. Res., 52(4), 662 (2000)
Kang HY, Jung MJ, Jung YK, Korean J. Biotechnol. Bioeng,, 15(5), 521 (2000)
http://www.standard.go.kr/skin3/default.asp?ebook_path=/KS_EBOOK_DN/&ebook_name=KSM0146_2003_04.htm
Chung HM, Inst. Glob. Envi., 9, 71 (1998)
Tomioka Y, Miyaji T, Oka H, Tomita K, Nishino A, J. Antibact. Antifug Agents, 21(9), 503 (1993)
Shin CH, Jung SH, Park DK, J. KSEE, 19(2), 177 (1997)
Lee JI, Shin CH, Park DK, J. KSEE, 17(2), 137 (1195)
Hill WR, Pillsbury DM, the Pharmacology of Silver, The Williams & Wilkins Co., Baltimore (1973)
Davies RL, Etris SF, Catal. Today, 36(1), 107 (1997)
Cecil WC, Charles MP, Paul WK, J. AWWA, 54, 208 (1962)
Richard LW, J. AWWA, 55, 881 (1963)
Feng QL, Wu J, Chen GQ, Cui FZ, Kim JO, Biomed. Mat. Res., 52(4), 662 (2000)
Kang HY, Jung MJ, Jung YK, Korean J. Biotechnol. Bioeng,, 15(5), 521 (2000)
http://www.standard.go.kr/skin3/default.asp?ebook_path=/KS_EBOOK_DN/&ebook_name=KSM0146_2003_04.htm
Chung HM, Inst. Glob. Envi., 9, 71 (1998)
