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Language: korean

Conflict of Interest: In relation to this article, we declare that there is no conflict of interest.

Publication history: Received December 20, 2007
Accepted February 11, 2008

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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도라지 추출물로부터 천연계면활성제의 개발

Development of a Natural Surfactant from Extracts of Platycodon Grandiflorum

김희진 박숙경¹ 김보영 홍슬기 조성기 김동욱^†

Hee Jin Kim Suk Kyong Park¹ Bo Young Kim Seul-Ki Hong Sung Ki Cho Donguk Kim^†

인제대학교 제약공학과, 621-749 경남 김해시 어방동 607 ¹코리아나 화장품, 330-833 충남 천안시 성거읍 정촌리 204-1

Department of Pharmaceutical Engineering, Inje University, 607 Obang-dong, Gimhae, Gyongnam 621-749, Korea ¹Coreana Cosmetics, 204-1 Jeongchon-ri, Seonggeo-eup Cheonan, Chungnam 330-833, Korea

pedkim@inje.ac.kr

Korean Chemical Engineering Research, April 2008, 46(2), 227-232(6), NONE Epub 29 May 2008

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Abstract

화장품용 천연계면활성제를 개발하기 위해 도라지(platycodon grandiflorum) 껍질에서 유기용매를 이용하여 추출물을 얻었다. 도라지 추출물의 화장품용 계면활성을 측정하기 위해 계면장력, 용해도, 기포력, 분산력, 유화력, 유화활성, 유화안정성을 측정하였고 피부자극을 평가하기위해 첩포시험을 실시하였다. 도라지 사포닌 함량이 0.005 wt%일 때 castor oil에 대한 계면장력은 11.5 dyn/cm로 비교대상인 Tween 40이나 quillaja bark보다 낮은 계면활성을 보여주었다. 도라지 추출물은 화장품에 유상으로 사용되는 olive oil, soybean oil, canola oil에 대해서도 우수한 유화활성과 유화안정성을 나타내었다. 2~5%의 도라지 추출물과 글리세린을 사용한 피부자극 시험에서는 도라지 추출물은 약간의 피부자극을 보여 주었다. 결론적으로 도라지 추출물은 화장품용 계면활성력은 양호하나 다소의 피부자극을 보여주었다.

In this research, organic extracts from roots of platycodon grandiflorum was tested to see the possibility for cosmetic natural surfactant. Interfacial properties of extracts of Platycodon grandiflorum was checked for interfacial tension, forming force, dispersion force, emulsion force, emulsion activity, and emulsion stability. At 0.005 wt% concentration, the interfacial tension against the caster oil was 11.5 dyn/cm which was lower than that of Tween 40 and quillaja bark. Extracts of Platycodon grandiflorum showed excellent emulsification activity and stability for cosmetic oils such as olive oil, soybean oil, and canola oil. In patch test using 2-5% of the extract and glycerin, the extract showed mild skin irritation. From the experiment, the extracts of platycodon grandiflorum root showed good interfacial properties as a cosmetic agent with minor skin irritation.

Keywords

Cosmetic Surfactant Platycodon Grandiflorum Emulsification Stability Surface Tension Skin Irritation

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