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- In relation to this article, we declare that there is no conflict of interest.
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Received July 31, 2017
Accepted December 15, 2017
- This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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치과용 인상재에서의 클로르헥시딘과 에센셜 오일의 항균성능에 대한 상승효과
Synergy Effect of Chlorhexidine and Essential Oils on Antimicrobial Activity in Dental Impression Materials
강원대학교 공과대학 화학공학과, 24341 강원도 춘천시 강원대학길1
Department of Chemical Engineering, Kangwon National University, 1, Gangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341, Korea
krlee@kangwon.ac.kr
Korean Chemical Engineering Research, April 2018, 56(2), 240-244(5), 10.9713/kcer.2018.56.2.240 Epub 5 April 2018
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Abstract
There is growing concern about cross infection among the patients to patients, patients to staffs, and tools to patients in healthcare facilities, especially in dentistry. In this study, the most widely used dental impression materials were prepared and the synergy effect of Chlorhexidine and essential oil on antimicrobial activity was examined in the impression materials. Chlorhexidine concentration of 0.1 wt% and 0.5 wt% showed no antimicrobial activity on Escherichia coli (E. coli) and Candida albicans. At 1.0 wt% Chlorhexidine, 0% of E. coli and 34.7% of Candida albicans were survived. Bergamot (Essential oil) concentration of 0.5 wt% and 1.0 wt% showed no antimicrobial activity on E. coli. At 2.0 wt% Bergamot oil, 71.9% of E. coli were survived. Tea tree oil (Essential oil) of 0.5 wt% showed no antimicrobial activity on E. coli. At 1.0 wt% Tea tree oil, 11.2% of E. coli was survived. At 2.0 wt% Tea tree oil, no E. coli was survived. However, no E. coli was survived at the concentration of 0.8 wt% Bergamot with 0.3 wt% Chlorhexidine. At the concentration of 0.8 wt% Tea Tree oil with 0.3 wt% Chlorhexidine, 1.3% of E. coli were survived. The experimental results showed that the synergy effects between Chlorhexidine and essential oils on antimicrobial activity were prominent.
Keywords
References
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Flanagan DA, Palenik CJ, Setcos JC, Miller CH, Dental Materials, 14(6), 399 (1998)
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Silla MP, Company JMM. Silla JMA, Med. Oral Patol. Oral Cir. Bucal., 13, E257 (2008)
McDonnell G, Russell AD, Clin. Microbiol. Rev, 12, 147 (1999)
Holley RA, Patel D, Food Microbiol., 22, 273 (2005)
Helander IM, Alakomi HL, Latva-Kala K, Mattila-Sandholm T, Pol I, Smid EJ, Gorris LGM, Wright AV, J. Agric. Food Chem., 46, 3590 (1998)
Rasooli I, Rezaei MB, Allameh A, Int. J. Infect. Dis., 10, 236 (2006)
Smith-Palmer A, Stewart J, Fyfe L, Lett. Appl. Microbiol., 26, 122 (1998)
Delaquis PJ, Stanich K, Girard B, Mazza G, Int. J. Food Microbiol., 74, 101 (2002)
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Southwell IA, Hayes AJ, Markham JL, Leach DN, Acta Hort., 334, 265 (1993)
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Trumpower BL, Gennis RB, Annu. Rev. Biochem., 63, 675 (1994)