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Received May 5, 2020
Accepted May 30, 2020
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스트레스 내성 식물 호르몬인 앱시스산의 산업적 활용 전망
Future Prospects for Industrial Application of Abscisic acid, a Stress-resistant Phytohormone
상명대학교 생명공학과, 03016 서울시 종로구 홍지문 2길 20
Department of Biotechnology, Sangmyung University, 20, Hongjimun 2-Gil, Jongno-Gu, Seoul, 03016, Korea
Korean Chemical Engineering Research, November 2020, 58(4), 514-523(10), 10.9713/kcer.2020.58.4.514 Epub 29 October 2020
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Abstract
이동성이 없는 식물은 주위 환경에서 다양한 형태의 스트레스를 받게 되는데 이를 대응하기 위한 방어 기작으로 스트레스 저항성 단백질과 조절 단백질이 생성된다. 앱시스산은 이러한 신호전달 역할을 하는 호르몬 분자로 잘 알려져 있으며, 잎의 노화, 종자의 휴면 등 식물의 생리적 반응에도 관여한다. 특히 식물이 아닌 동물, 조류(algae) 등 다른 생물계에서도 다양한 기능을 수행하는 것으로 밝혀졌다. 본 총설에서는 앱시스산의 생합성 및 신호전달 과정 그리고 그 기능에 대하여 조사하였고, 농생명공학, 의생명공학, 산업생명공학을 포함한 다양한 생명공학분야에서 앱시스산을 활용한 작물량 증대, 질병 치료제 개발, 바이오에너지 생산 등 최신 응용 연구 및 산업적 활용에 대한 동향을 살펴보았다.
Plants are exposed to various types of stresses in their surroundings, and stress-resistant and regulatory proteins are produced as defense mechanisms. Abscisic acid is well known for its important role in stress signals as a phytohormone and is also involved in the physiological reactions of plants such as leaf senescence and seed dormancy. In particular, it has been found to perform a variety of functions in other biological systems, such as animals and microalgae, not plants. In this review, the biosynthesis and signaling process of abscisic acid and its function were investigated and the future prospects for the industrial application of abscisic acid in various biotechnologies, including agriculture, biomedical and industrial biotechnology, have been proposed based on study of emerging applications such as increased crop yields, disease treatment development and bioenergy production.
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Atkinson NJ, Urwin PE, J. Exp. Bot., 63(10), 3523 (2012)
Addicott FT, Lyon JL, Ohkuma K, Thiessen WE, et al., Science, 159(3822), 1493 (1968)
Strausz SD, Ph.D. Dissertation, Oregon State University, Corvallis, Oregon(1970).
Cornforth JW, Milborrow BV, Ryback G, Rothwell K, Wain RL, Nature, 211(5050), 742 (1966)
Zhang XL, Jiang L, Xin Q, Liu Y, Tan JX, Chen ZZ, Front. Plant Sci., 6, 88 (2015)
Sah SK, Reddy KR, Li J, Front. Plant Sci., 7, 571 (2016)
Lawas LMF, Zuther E, Jagadish SK, Hincha DK, Curr. Opin. Plant Biol., 45, 212 (2018)
Pareek A, Dhankher OP. Foyer CH, J. Exp. Bot., 71(2), 451 (2020)
Ray S, Mondal WA, Choudhuri MA, Physiol. Plant., 59(3), 343 (1983)
Kang J, Yim S, Choi H, Kim A, Lee KP, Lopez-Molina L, Martinoia E, Lee Y, Nat. Commun., 6(1), 8113 (2015)
Kobayashi Y, Tanaka K, Bio Protoc., 6(23), e2033 (2016)
Balino P, Gomez-Cadenas A, Lopez-Malo D, Romero FJ, Muriach M, Antioxidants, 8(4), 104 (2019)
Finkelstein R, Arabidopsis Book, 11, e0166 (2013)
Xiong L, Zhu JK, Plant Physiol., 133, 29 (2003)
Vishwakarma K, Upadhyay N, Kumar N, Yadav G, et al., Front. Plant Sci., 8, 161 (2017)
Saroj KS, Kambham RR, Jiaxu L, Front. Plant Sci., 7, 571 (2016)
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Muller AH, Hansson M, Plant Physiol., 150(1), 157 (2009)
Tsuzuki T, Takahashi K, Inoue S, Okigaki Y, et al., J. Plant Res., 124(4), 527 (2011)
Wang XF, Zhang DP, Ann. Bot., 101(3), 311 (2008)
Pandey S, Nelson DC, Assmann SM, Cell, 136(18), 136 (2009)
Park SY, Fung P, Nishimura N, Jensen DR, Fujii H, et al., Science, 324(5930), 1068 (2009)
Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A, Grill E, Science, 324(5930), 1064 (2009)
Lin CW, Baek W, HAn SW, Lee SC, Plant Pathol. J., 29(4), 471 (2013)
Qiu J, Hou Y, Wang Y, Li Z, Zhao J, Tong X, Lin H, Wei X, Ao H, Zhang J, Int. J. Mol. Sci., 18, 60 (2017)
Tischer SV, Wunschel C, Papacek M, Kleigrewe K, Hofmann T, Christmann A, Grill E, Proc. Natl. Acad. Sci. USA, 114(38), 10280 (2017)
Khan ZH, Kumar B, Dhatterwal P, Mehrotra S, Mehrotra R, Int. J. Plant Biol. Res., 5(2), 1064 (2017)
Nakashima K, Suenaga K, Jpn. Agric. Res. Q., 51(1), 1 (2017)
Pei ZM, Ghassemian M, Kwak CM, McCourt P, Schroeder JI, Science, 282(5387), 287 (1998)
Zeevaart JAD, Creelman RA, Annu. Rev. Plant Physiol., 39(1), 439 (1988)
Osakabe Y, Osakabe K, Shinozaki K, Tran JP, Front. Plant Sci., 5, 86 (2014)
Darwin F, Philos. Trans. Royal Soc., 190, 531 (1898)
Bauer H, Ache P, Lautner S, Fromm J, Hartung W, et al., Curr. Biol., 23(1), 53 (2013)
Mori IC, Schroeder JI, Plant Physiol., 135(2), 720 (2004)
Joshi-Saha A, Valon C, Leung J, Sci. Signal, 4(201), re4 (2011)
Munemasa S, Hauser F, Park J, Waadt R, Brandt B, Schroeder JI, Curr. Opin. Plant Biol., 28, 154 (2015)
Lisar SY, Motafakkerazad R, Hossain MM, Rahman IMM, Water Stress, InTech, Croatia (2012).
Van der Graaff E, Schwacke R, Schneider A, Desimone M, Flugge UI, Kunze R, Plant Physiol., 141(2), 776 (2006)
Himelblau E, Amasino RM, J. Plant Physiol., 158(10), 1317 (2001)
Asad MAU, Zakari SA, Zhao Q, Zhou L, Ye Y, Cheng F, Int. J. Mol. Sci., 20(2), 256 (2019)
Riov J, Dagan E, Goren R, Yang SF, Plant Physiol., 92(1), 48 (1990)
Zhao Y, Chan Z, Gao J, Xing L, Cao M, Yu C, Hu Y, You J, et la., Proc. Natl. Acad. Sci. USA, 113(7), 1949 (2016)
Zhao Y, Gao J, Kim GI, Chen K, Bressan RA, Zhu JK, Plant Cell Physiol., 58(8), 1319 (2017)
Huo H, Dahal P, Kunusoth K, McCallum CM, Bradford KJ, Plant Cell, 25(3), 884 (2013)
Martinez-Andujar C, Ordiz MI, Huang Z, Nonogaki M, Beachy RN, Nonogaki H, Proc. Natl. Acad. Sci. USA, 108(41), 17225 (2011)
Vishal B, Kumar PP, Front. Plant Sci., 9, 838 (2018)
Cowan AK, Rose PD, Plant Physiol., 97(2), 798 (1991)
Lee KW, Hong S, Rahman MA, Ji HC, Cha JY, Jones CS, Son D, Lee S, Biotechnol. Bioprocess Eng., 24(3), 552 (2019)
Brito C, Dinis LT, Ferreira H, Moutinho-Pereira J, Correia CM, Plants, 9(3), 341 (2020)
He J, Jin Y, Palta JA, Liu HY, Chen Z, Li FM, Agronomy, 9(7), 395 (2019)
Takeuchi J, Okamoto M, Mega R, Kanno Y, Ohnishi T, Seo M, Todoroki Y, Sci. Rep., 6(1), 37060 (2016)
Okazaki M, Nimitkeatkai H, Muramatsu T, Aoyama H, Ueno K, et al., Bioorg. Med. Chem., 19(1), 406 (2011)
Okazaki M, Kittikorn M, Ueno K, Mizutani M, Hirai N, Kondo S, Ohnishi T, Todoroki Y, Bioorg. Med. Chem., 20(10), 3162 (2012)
Han S, Min MK, Lee SY, Lim CW, Bhatnagar N, et al., Mol. Plant, 10(9), 1190 (2017)
Richardson WC, Badrakh T, Roundy BA, Aanderud ZT, et al., Ecol. Evol, 9, 7438 (2019)
Badrakh T, MSc Dissertation, Brigham Young University, Provo, Utah(2016).
Lievens L, Pollier J, Goossens A, Beyaert R, Staal J, Front. Plant Sci., 8, 587 (2017)
Guri AJ, Evans NP, Hontecillas R, Bassaganya-Riera J, J. Nutr. Biochem., 22(9), 812 (2011)
Li HH, Hao RL, Wu SS, Guo PC, Chen CJ, Pan LP, Ni H, Biochem. Pharmacol., 82(7), 701 (2011)
Zocchi E, Hontecillas R, Leber A, Einerhand A, Carbo A, et al., Front. Nutr., 4, 24 (2017)
Bruzzone S, Moreschi I, Usai C, Guida L, Damonte G, et al., Proc. Natl. Acad. Sci. USA, 104(14), 5759 (2007)
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA, J. Biol. Chem., 270(22), 12953 (1995)
Guri AJ, Hontecillas R, Si H, Liu D, Bassaganya-Riera J, Clin. Nutr., 26(1), 107 (2007)
Magnone M, Emionite L, Guida L, Vigliarolo T, Sturla L, et al., Sci. Rep., 10(1), 1454 (2020)
Weller J, Budson A, F1000Res., 7, 1161(2018).
Kinney JW, Bemiller SM, Murtishaw AS, Leisgang AM, Lamb BT, Alzheimers Dement, 4, 575 (2018)
Biundo F, Del Prete D, Zhang H, Arancio O, D'Adamio L, Sci. Rep., 8(1), 3184 (2018)
Govindarajulu M, inky PD, Bloemer J, Ghanei N, Suppiramaniam V, Amin R, PPAR Res., 2018, 201067 (2018)
Prakash A, Kumar A, Neurotox. Res., 25(4), 335 (2014)
Liu J, Gu X, Zou R, Nan W, Yang S, Wang HL, Chen XT, Front. Pharmacol., 9, 1141 (2018)
Lee KS, Lee YJ, Chang HN, Jeong KJ, Korean J. Chem. Eng., 36(6), 903 (2019)
Joshi R, Singla-Pareek SL, Pareek A, J. Biol. Chem., 293(14), 5035 (2018)
Rahpeyma SS, Raheb J, Bioenergy Res., 12(4), 958 (2019)
Ju JH, Oh BR, Ryu SK, Heo SY, Kim SY, Hong WK, Kim CH, Seo JW, Biotechnol. Bioprocess Eng., 23(6), 726 (2018)
Choi YY, Hong ME, Chang WS, Sim SJ, Biotechnol. Bioprocess Eng., 24(1), 223 (2019)
Lee JH, Lee HU, Lee JH, Lee SK, Yoo HY, Park CH, Kim SW, Korean J. Chem. Eng., 36(1), 71 (2019)
Muthuraj M, Selvaraj B, Palabhanvi B, Kumar V, Das D, Korean J. Chem. Eng., 36(1), 63 (2019)
Contreras-Pool PY, Peraza-Echeverria1 S, Ku-Gonzalez AF, Herrera-Valencia VA, ALGAE, 31(3), 267 (2016)
Sulochana SB, Arumugam M, Bioresour. Technol., 213, 198 (2016)
Sulochana SB, Arumugam M, Bioresour. Technol., 213, 198 (2016)
Lu Y, Tarkowska D, Tureckova V, Luo T, Xin Y, Li J, et al., Plant J., 80(1), 52 (2014)
Lin B, Ahmed F, Du H, Li Z, Yan Y, Huang Y, Ciu Y, Yin Y, Li B, Wang M, Meng C, Gao Z, J. Appl. Phycol., 30, 1549 (2017)
Sivaramakrishnan R, Incharoensakdi A, Biotechnol. Biofuels, 13(7), 1 (2020)