전세계적으로 천연화장품에 대한 관심과 수요가 크게 늘어나고 있다. 따라서 기존 화학합성 기능성화장품소재를 대 체하기 위한 노력의 일환으로서 천연물에서 기능성화장품소재를 발굴하고자 하였다. 모자반은 우리나라의 해안 전지 역에서 쉽게 볼 수 있는 갈조류의 일종으로서 식용으로도 이용되는 만큼 안전성이 확보되어있는 해조류이다. 본 연구 에서는 큰잎 모자반(Sargassum coreanum). 짝잎 모자반(Sargassum hemiphyllum), 쌍발이 모자반(Sargassum patens) 의 3가지 종류의 모자반으로부터 열수를 이용하여 유효성분을 추출하였으며, 항산화효과, 미백효과, 주름개선효과, 자 외선흡수효과 및 항염증효과를 측정하여 기능성 화장품 소재로서의 응용 가능성을 살펴보고자 하였다. 모자반추출물 은 세포독성시험결과 안전성이 매우 우수하였고, DPPH radical scavenging activity를 이용한 항산화능 측정결과 우수 한 항산화능을 보여주었으며 tyrosinase inhibition을 이용한 미백효과시험에서는 큰잎 모자반(Sargassum coreanum)의 미백효과가 상당히 우수하였다. 그러나 주름개선효과, 자외선흡수효과와 항염증효과는 비교적 낮았다. 결론적으로 큰 잎 모자반(Sargassum coreanum)은 세포독성이 적었고, 항산화효과와 미백효과가 우수하여 미백 기능성화장품소재로서 응용가능성이 높음을 알 수 있었다.

There is growing interest in natural cosmetic ingredients as natural cosmetics become popular. As a part of effort to look for natureal cosmetic agent, seaweed Sargassums were tested for functional cosmetic agents. Effective materials were extracted from Sargassum coreanum. Sargassum hemiphyllum, and Sargassum patens by simple hot water extraction. Antioxidation, whitening, anti-wrinkle, UV absorption and anti-inflammation effects were studied for functional cosmetic agents. Sargassum extracts indicated excellent cell viability, strong anti-oxidation effect by DPPH radical scavenging activity and showed significant whitening effect from tyrosinase inhibition. However, effects of antiwrinkle, UV absorption and anti-inflammation were negligible. In conclusion, Sargassum coreanum extracts showed good possibility for anti-oxidation and whitening cosmetic agent.

Sargassum Extracts, Cell viability, Anti-oxidation, Whitening, Anti-wrinkle

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