This review examines the effects of different process parameters on the production of lactic acid.

Especially focusing on the factors such as, pH, temperature, utilization of fungi, viz., Rhizopus species and selection of

carbon and nitrogen sources. The development of lactic acid synthesis is promoted by acidic environment, usually

falling within pH < 3.5, which allows optimal lactic acid synthesis. Another important factor is temperature. Strains

such as lactobacillus rhamnosus DUT1908, have a high tolerance to temperature as high as 50℃, which allows for

effective substrate utilization and high lactic acid yield. This review highlights the need of tailoring these process

parameters to the specific characteristics of the biomass and the metabolic pathways of the microorganisms to achieve

increased lactic acid production.

Fermentation, Thermophilic microorganisms, Yeast, Fungi, Enzymes

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