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Received March 5, 2009
Accepted March 31, 2009
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Characterization of PVA/glycerin hydrogels using γ-irradiation for advanced wound dressings
Young-Chang Nho1†
Youn-Mook Lim1
Sung-Jun An1
Min-Ho Youn1
Seol-Hee Han1
Ho-Nam Chang2
Hui-Jeong Gwon1 2
1Radiation Research Center for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong, Jeongeup-si, Jeonbuk 580-185, Korea 2Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science Technology, Daejeon 305-701, Korea
Korean Journal of Chemical Engineering, November 2009, 26(6), 1686-1688(3), 10.1007/s11814-009-0246-z
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Abstract
The aim of this study was to investigate the enhanced absorption property of PVA/Glycerin (PVA/Gly) hydrogel for advanced wound dressing. A simple crosslinking method was introduced to prepare the PVA/Gly hydrogels with the use of γ-irradiation. An absorption ratio and thermal properties of the PVA/Gly hydrogels can be controlled by varying the irradiation dose and weight ratio of the PVA/Gly. When the PVA/Gly content was 20/5 wt% and the irradiation dose at 25 kGy, the PVA/Gly hydrogels showed excellent absorption properties (>350%). These results imply_x000D_
that the PVA/Gly hydrogel is highly absorbent and converts wound exudates to the hydrogel matrices that create a moist and clean environment in the wound healing process. Therefore, the PVA/Gly hydrogel prepared by this method can be used as an advanced wound dressing.
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