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- In relation to this article, we declare that there is no conflict of interest.
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Received December 26, 2005
Accepted January 31, 2006
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치마버섯 유래 다당체의 화상 및 상처 치유효과
Effect of Polysaccharide from Schizophyllum commune on Burn and Wound Healing
강원대학교 생물공학과, 200-701 강원도 춘천시 효자 2동 192-1
Department of Bioengineering & Technology, Kangwon National University, 192-1, Hyoja-2-dong, Chuncheon, Kangwondo 200-701, Korea
ekhong@kangwon.ac.kr
Korean Chemical Engineering Research, February 2006, 44(1), 87-91(5), NONE Epub 9 March 2006
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Abstract
버섯 유래 다당체는 항암관련 면역활성이 매우 우수하다고 밝혀지고 있다. 이러한 다당체는 화상이나 상처에 의해 야기된 괴사조직 제거와 손상된 상피조직 재생에 관여하는 피부 면역체계를 활성화시킴으로써 치유 효과가 탁월하다고 알려지고 있다. 더욱이 다당체는 생물고분자로서 보습 효과가 우수하여 재생된 상피조직의 2차 감염 및 가피 생성을 억제하는 효과가 있다. 따라서 본 연구에서는 보습 효과와 면역활성이 우수한 치마버섯 유래 다당체를 이용하여 in vivo 실험 및 혈액학적 검사를 통하여 화상 및 상처치유 효과를 검토하였다. 더불어 2차 감염을 유발하는 병원성 미생물의 생육 정도를 검토하여 항균 활성을 확인하였다.
Polysaccharides extracted from mushroom have been most commonly used to enhance the immune system. Also polysaccharides maintaining the moisture extent on epidermal tissue have an effect on the removal of necrotic tissue and the restoration of epidermal tissue through enhancing the immune system at skin layers. In this work, polysaccharides were from Schizophyllum commune studied about the burn and wound healing activity in the epidermal tissue on rats through in vivo experiment and hematological values. And antibacterial activities were examined using pathogenic microorganisms causing the secondary inflammation.
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